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Gc-Ms Analysis And In Vitro Antibacterial Activity Of The Essential Oil Of Cinnamodendron dinisii Schwacke (Canellaceae) Against Multirresistant Strains

  • 151-160
  • 17/02/2023
  • 17/02/2023
Pereira MJA;
Rocha JE;
de Freitas TS;
do Amaral W;
Deschamps C;
Confortin C;
da Silva LE;
da Costa JGM;
Coutinho HDM;
Colares AV

Maria Juliana Alves Pereira

Janaína Esmeraldo Rocha

Thiago Sampaio de Freitas

Wanderlei do Amaral

Cícero Deschamps

Camila Confortin

Luiz Everson da Silva

José Galberto Martins da Costa

Henrique Douglas Melo Coutinho

Aracelio Viana Colares

Resumo

Medicinal plants are used as cheaper alternatives for the treatment of certain pathologies. Due to the great Brazilian biodiversity, many plants do not have in-depth studies such as Cinnamodendron dinisii Schwacke (pepper or pau-pra-tudo), which is native to the south and southeast. The aim of this study was to evaluate the antibacterial activity of Cinnamodendron dinisii Schwacke essential oil (OECd) against multiresistant strains: Escherichia coli 06 (EC 06) and Staphylococcus aureus (SA 10). Ampicillin, Norfloxacin and Gentamicin were diluted in distilled water and used for the modulatory test. The tests followed the methodology of microdilution in broth to obtain the Minimum Inhibitory Concentration (MIC). The MIC/8 of the products was used in the resistance reversal test. In terms of direct activity, OECd showed the best result against S .aureus with a MIC of 512µg/mL. For bacterial resistance reversal tests, OECd showed better synergistic interactions with the antibiotics ampicillin and gentamicin, both against E.coli strains. The results demonstrate that OECd has antibacterial action when tested alone or in combination with antibiotics against multidrug-resistant strains.

 

DOI: https://doi.org/10.56238/methofocusinterv1-100

Creative Commons License

Este trabalho está licenciado sob uma licença Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Copyright (c) 2023 Maria Juliana Alves Pereira, Janaína Esmeraldo Rocha, Thiago Sampaio de Freitas, Wanderlei do Amaral, Cícero Deschamps, Camila Confortin, Luiz Everson da Silva, José Galberto Martins da Costa, Henrique Douglas Melo Coutinho, Aracelio Viana Colares
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##plugins.themes.gdThemes.article.Authors##

  • Maria Juliana Alves Pereira
  • Janaína Esmeraldo Rocha
  • Thiago Sampaio de Freitas
  • Wanderlei do Amaral
  • Cícero Deschamps
  • Camila Confortin
  • Luiz Everson da Silva
  • José Galberto Martins da Costa
  • Henrique Douglas Melo Coutinho
  • Aracelio Viana Colares