FACTOR V LEIDEN MUTATION AND PROTHROMBIN GENE ASSOCIATED WITH INTRACRANIAL VENOUS THROMBOSIS: A CASE REPORT

Authors

  • Renan da Silva Bentes
  • Marcelo Caetano Hortegal Andrade Andrade
  • Matheus Mychael Mazzaro Conchy
  • Elias José Piazentin Gonçalves Junior
  • Tauaní Coelho Nabuco de Araújo Souza
  • Lúcio Elber Licarião Távora
  • Márcio Tiago de Oliveira Barbosa

Keywords:

Intracranial Venous Thrombosis (TVI), Factor V Leiden (MFVL) mutation, Mutation in the Prothrombin Gene (PM), Ischemic optic neuropathy (ION), Combined contraceptives (ACO)

Abstract

Intracranial venous thrombosis is an uncommon event with high morbidity and mortality. This article aims to present a case of intracranial venous thrombosis associated with mutation of factor V Leiden and mutation in the prothrombin gene after contraceptive use that culminated in ischemic optic neuropathy and permanent total bilateral amaurosis. Early diagnosis and treatment are essential for patient survival and relevant genetic screening for clinical counseling and, thus, to avoid new thrombotic episodes of great clinical repercussion in female individuals.

DOI: https://doi.org/10.56238/sevened2025.008-038

Published

2025-03-24

How to Cite

FACTOR V LEIDEN MUTATION AND PROTHROMBIN GENE ASSOCIATED WITH INTRACRANIAL VENOUS THROMBOSIS: A CASE REPORT. (2025). Seven Editora, 587-594. https://sevenpublicacoes.com.br/editora/article/view/6824