Phytochemical study and biological activity of the bark of the stem of the plant species araticum bravo (Annona tomentosa R. E. Fr.)
Keywords:
Annonaceae, Phytochemical screening, Antimicrobial activity.Abstract
Annona tomentosa R. E. Fr. (Annonaceae), known in Brazil as Araticum-bravo or Araticum de moita, is a small tree found throughout the Brazilian territory, mainly in coastal areas, its distribution is discontinuous, appearing in open fields, in the cerrado of shrubby trees and in the cerradão, where the vegetation is denser. All parts of this vegetable are used in folk medicine, it has been used mainly to combat diarrhea, stomatitis, headache, neuralgia, boils, ulcers and in the eradication of lice in addition to antirheumatics. Based on data obtained by
In a bibliographic survey, this work sought information of chemical natures, through phytochemical and microbiological screening by antimicrobial activity tests. In the phytochemical screening, the presence of substances belonging to the classes of phenols, tannins, anthocyanins, anthocyanidin, flavonoids, xanthones, saponins, steroids, triterpenes and alkaloids were confirmed. Confirmation for alkaloids was performed by chromatoplates. Standard strains (ATCC) of Gram-positive Staphylococcus aureus 25923 bacteria and Gram-negative bacteria were used to evaluate the antimicrobial activity
Pseudomonas aeruginosa 27853, Escherichia coli 35218, Klebsiella pneumoniae 700603. Clinical isolates of Acinectobacter baumannii and the fungus Candida albicans were used in the microbiological tests. The antimicrobial potential of the extract was analyzed by the technique of perforation in Müller Hinton medium, the results showed that the peels of A. tomentosa have an inhibitory potential of growth on the Gram-positive bacterium, S. aureus, and on the clinical microorganisms with emphasis on A. baumanni with halo formation of (20mm) respectively.
