Minimally invasive animal model for bone implant in swine

Abstract

Objective: The present study aimed to develop a minimally invasive animal model that could accommodate evaluation experiments for cortico-spongy implants in the areas of orthopedics, dentistry, and neurology. Methodology: On the anteromedial surface of the proximal third of the tibia of pigs, we have a cortico-spongy area that is basically subcutaneous. This region proved to be ideal for this purpose. Results and discussions: The pig is already a well-known animal for testing biomaterials in bones because its bone regeneration rate (1.2 and 1.5 mm/d) is comparable to that of humans (1.0 and 1.5 mm/d) Conclusion: The Animal Model was formatted, which proved to be simple and reproducible.

DOI:https://doi.org/10.56238/uniknowindevolp-073