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Creatine and physical resistance exercises: positive effects and changes in the years: an integrative review

Limaverde Gomes I;
Pinheiro Pereira C;
Nogueira Bezerra A;
Carolina Amancio L;
Pinheiro Cavalcante K;
Pereira Aguiar L;
Pereira BB;
Henrique Bernardino De Freitas P;
Pereira Souza G;
Teixeira Terceiro Paim R

Isabela Limaverde Gomes

Camila Pinheiro Pereira

Alane Nogueira Bezerra

Livia Carolina Amancio

Karla Pinheiro Cavalcante

Larissa Pereira Aguiar

Bruno Barros Pereira

Pedro Henrique Bernardino De Freitas

Gustavo Pereira Souza

Raquel Teixeira Terceiro Paim


Keywords

creatine supplementation
creatine and physical exercise.

Abstract

A supplement widely used in resistance training is creatine, which is composed of three amino acids (arginine, glycine, and methionine). It is found primarily in skeletal muscle (95%) and plays an important role in the rapid supply of energy during muscle contraction via the ATP-CP system. Because of this, in this study, an integrative literature review was carried out, to understand the positive effects and renal changes of creatine in physical exercises. The research was carried out between September 2021 and May 2022, with searches in PubMed and Scielo databases. The following descriptors from the DeCS (descriptors in health science created by BIREME) and MESH (medical subject headings) were used: "creatine supplementation", "dose-dependent creatine", "creatine", "Creatine Supplementation and Exercise Training". Most studies have shown that creatine supplementation (CR) is important for resistance training and muscle performance and is an effective resource in increasing energy, as creatine is involved in one of the metabolic energy delivery systems, in which Adenosine bisphosphonates (ADP) are enzymatically linked to phosphocreatine (CP) to regenerate adenosine triphosphate (ATP), the main energy currency. After creatine supplementation, there is more CR in the muscles, which favors an increase in energy supply through ATP resynthesis.

DOI: https://doi.org/10.56238/devopinterscie-128


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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Copyright (c) 2023 Isabela Limaverde Gomes, Camila Pinheiro Pereira , Alane Nogueira Bezerra, Livia Carolina Amancio, Karla Pinheiro Cavalcante, Larissa Pereira Aguiar, Pedro Henrique Bernardino De Freitas, Gustavo Pereira Souza, Raquel Teixeira Terceiro Paim

Author(s)

  • Isabela Limaverde Gomes
  • Camila Pinheiro Pereira
  • Alane Nogueira Bezerra
  • Livia Carolina Amancio
  • Karla Pinheiro Cavalcante
  • Larissa Pereira Aguiar
  • Bruno Barros Pereira
  • Pedro Henrique Bernardino De Freitas
  • Gustavo Pereira Souza
  • Raquel Teixeira Terceiro Paim