APPLICATIONS OF HYDROXYAPATITE IN BONE REPAIR: ADVANCES, CHALLENGES AND PERSPECTIVES: AN INTEGRATIVE REVIEW

Abstract

Hydroxyapatite represents a natural bioceramic that acts in the repair of hard bone tissue in mammals. This work aims to review the literature on applications of hydroxyapatite in bone repair. An integrative review was carried out in the Scopus, Medline and SciELO databases, by crossing the terms Bone Regeneration AND Hydroxyapatite AND biopolymer. Initially, 201 documents were identified, including freely accessible articles available for full reading in english and Portuguese, works published between 2017 and 2023, and excluding duplicate studies and those with low reliability methodologies and works that did not fit the theme. proposed, 5 articles were selected to compose the sample. As a result, three main categories of alternative materials found application in the clinical context were highlighted, notably in procedures related to bone tissue. These categories include allografts (transplants between individuals of the same species), xenografts (transplants between different species) and alloplastic materials (synthetically produced, which demonstrate remarkable biocompatibility, efficacy in promoting osteoconduction, bone repair and microbiological control. In addition, the evaluation of This comparison highlights the importance of careful selection of biomaterials, considering not only their origin but also their specific properties. In conclusion, although these studies provide an optimistic outlook for the future of bone regeneration, it is imperative to conduct further clinical research to validate these findings, ensuring its broad applicability and long-term safety in patients.

DOI:  https://doi.org/10.56238/sevened2025.020-025