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EXPLANTATION BY OSTEONECROSIS AFTER WISDOM TOOTH EXTRACTION

de Oliveira JEP;
de Souza VZ;
de Souza GB;
de Andrade TI;
Vieceli EP;
Figueiredo FC;
Garcia GF;
Manfro R

José Eudes Protázio de Oliveira

Vilton Zimmermann de Souza

Gabriel Baldissera de Souza

Taysnara Ismaeley de Andrade

Eduardo Panceri Vieceli

Fábio Castanha Figueiredo

Gislaine Felipe Garcia

Rafael Manfro


Keywords

Antiresorption
Denosumab
Bisphosphonate-associated osteonecrosis
Bone resorption

Abstract

Osteonecrosis, defined as the death of bone tissue due to lack of blood supply, is a pathological condition that, associated with predisposing factors, can affect the gnathic bones, exacerbating the inflammatory process due to the wide oral microbiota, and can significantly affect the quality of life of patients. Patients with skeletal disorders that induce bone loss, such as osteoporosis, make continuous use of antiresorptive drugs in order to alter bone remodeling. The objective of this study is to describe a case report of the treatment of osteonecrosis of the jaws induced by denosumab, discussing clinical-pathological aspects of the disease.  This article highlights the case of patient R.S.B.K., 78 years old, who was affected by breast cancer, for whom she underwent chemotherapy treatment for 5 years. He suffered a pathological rib fracture, where he started treatment with an anti-resorptive drug called Denosunab. After dental extraction of element 28, a local infectious inflammatory process involving adjacent implants began, which culminated in unsuccessful surgical interventions. After the end of the half-life of the medication, the return of tissue functions was observed, evolving with bone coverage by the oral mucosa. It is concluded that the correct and early diagnosis is essential, combined with a resolutive treatment through a conservative approach, improving the quality of life of patients.

 

DOI:https://doi.org/10.56238/sevened2024.031-048


Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright (c) 2024 José Eudes Protázio de Oliveira, Marcelo Napimoga, Elisabeth Martinez, Dayane Peruzzo, Vilton Zimmermann de Souza, Taysnara Ismaeley de Andrade

Author(s)

  • José Eudes Protázio de Oliveira
  • Vilton Zimmermann de Souza
  • Gabriel Baldissera de Souza
  • Taysnara Ismaeley de Andrade
  • Eduardo Panceri Vieceli
  • Fábio Castanha Figueiredo
  • Gislaine Felipe Garcia
  • Rafael Manfro