GAMMA KNIFE AND QUALITY OF LIFE: A REVIEW OF THE USE OF RADIOSURGERY IN BRAIN TUMORS
Abstract
INTRODUCTION: In view of the quality of life of patients with brain tumors, several alternatives for treatment have been developed over time, aiming at a less invasive potential and providing a permanence in the individual's functional capacity. In this regard, in recent decades there has been debate about radiosurgery for the treatment of brain tumors. OBJECTIVE: The aim of this study was to evaluate the feasibility of Gamma Knife radiosurgery, with a view to patient safety. METHODS: This article is characterized as an integrative literature review of an exploratory nature, in the PubMED and Cochrane databases, the search was restricted to observational studies and randomized clinical studies as primary data for contemplation of the outcomes Quality of life, neurological preservation, recurrence, brain complications and overall survival. RESULTS: The analysis of the collected data showed that, in general, radiosurgery using the Gamma Knife platform preserves quality of life in several cases, especially in minor benign brain tumors. The rate of recurrence of the disease after 3 years of radiosurgery ranged from 20 to 40%, depending on the type of tumor and treatment, with the highest recurrence rate in grade III meningiomas and high-grade gliomas, the recurrence rate in 5 years ranged between 60 and 80%, and is therefore higher than more invasive treatments. CONCLUSION: The qualitative synthesis of these data proves the efficacy of radiosurgery and may suggest to neurosurgeons the possibility of treating brain tumors in patients not eligible for conventional surgery or for patients with non-bulky tumors.
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Copyright (c) 2024 João Victor Lemos Silva, Elton Lemos Silva, Atinelle Teles Novais Lemos, Joyce Damasio , Emanuelle Santos de Oliveira , Marlon Alexandre Ferreira Ribeiro , Leide Lourdes Barbosa Dias, Mayla Mikelly Amorim Maciel , Thalita de Cássia Silva de Oliveira , Leonardo Torres Camurça, Guillermo Cândido de Lorena, Weudson Cabral de França, Lucas Schneider, Luis Eduardo Rodrigues Barbosa , Rian Barreto Arrais Rodrigues de MoraisAuthor(s)
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João Victor Lemos Silva
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Elton Lemos Silva
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Atinelle Teles Novais Lemos
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Joyce Damasio
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Emanuelle Santos de Oliveira
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Marlon Alexandre Ferreira Ribeiro
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Leide Lourdes Barbosa Dias
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Mayla Mikelly Amorim Maciel
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Thalita de Cássia Silva de Oliveira
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Leonardo Torres Camurça
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Guillermo Cândido de Lorena
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Weudson Cabral de França
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Lucas Schneider
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Luis Eduardo Rodrigues Barbosa
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Rian Barreto Arrais Rodrigues de Morais