Study of the effect of calcination in obtaining nanostructured HAp by combustion reaction

Abstract

Human bone is made up of 9% water, 20% organic components, and 69% calcium phosphates. These phosphates are also present in the bone composition of different animal species, arousing great biological and medical interest, as it is a highly biocompatible material, that is, it could be compatible with living tissues and organic fluids without toxic effects or even immunological reactions. One of the most widely used representatives of the group of bioactive materials of calcium phosphate of synthetic origin is hydroxyapatite - HAp, Ca10(PO4)6(OH)2, due to its high osteinduction, which enables bone regeneration, structure and composition similar to that of phosphate present in skeletal tissue, also known as biological apatite, and its excellent biocompatibility. This research work proposed to study the influence of different calcination temperatures, within a predetermined range, combined with the use of two distinct fuels, glycine and urea, through the method of synthesis by combustion, in obtaining HAp formed by nanometric grains, so that its structure would be as similar as possible to biological apatite. For this investigation, the following techniques were used as methods of structural and morphological characterization: X-ray diffraction (XRD), energy dispersive spectroscopy (EDX), scanning electron microscopy (SEM) and thermogravimetry (TG). The results of the characterizations showed that using the two fuels it was possible to obtain the HAp phase, with grains of nanometric size forming heterogeneous clusters of easy deagglomeration, being the most efficient and with a higher degree of purity when using glycine, and calcined at 1200°C.

DOI:https://doi.org/10.56238/sevened2024.026-010