Chronic kidney disease in felines and the use of SDMA for diagnosis: Literature review
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Abstract
Due to the domestication process, tutors are increasingly concerned with ensuring better living conditions for their pets. This has reflected in the increased longevity of pets. Felines, due to anatomical, physiological and dietary aspects, have a certain predisposition to problems affecting the system renal.Com this, chronic kidney disease (CKD) is a progressive and irreversible disease, being an important cause of death in felines, especially with advanced age. Unfortunately, its initial signs are silent, becoming evident as the lesion progresses, thus allowing the worsening of the condition. Thus, when the diagnosis occurs, the evolution is already well established. Symmetrical dimethylarginine (SDMA) is a biomarker of renal function, correlated with glomerular filtration rate (TGF), and is used to evaluate the existence of Chronic Kidney Disease, because unlike the quantification of serum creatinine, it is not influenced by extrarenal mechanisms, for this reason it is considered more efficient. In 2015, SDMA became provisionally part of the International Society of Renal Interest (IRIS) classification of CKD as a complementary test of kidney function aiding in the classification of disease stages, thus allowing the identification of disease stages and substages. In this way, it is possible to better monitor and determine the most appropriate treatment for each patient.
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Copyright (c) 2024 Rafaela Cristina Cardoso Costa, Jaqueline Aparecida Sousa Pereira, Bruna Cardoso Lemes, Fátima Christina França Alexandrowitsch, Karine Pereira Silveira, Millena Baeta Jardim, Yasmin Jordana Arruda Brito, Nara Ladeira de Carvalho, Elizangela GuedesAuthor(s)
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Rafaela Cristina Cardoso Costa
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Jaqueline Aparecida Sousa Pereira
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Bruna Cardoso Lemes
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Fátima Christina França Alexandrowitsch
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Karine Pereira Silveira
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Millena Baeta Jardim
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Yasmin Jordana Arruda Brito
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Nara Ladeira de Carvalho
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Elizangela Guedes