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Management of statin-related muscle pain: Clinical strategies in patients at high cardiovascular risk

Silva EMA;
Guerra DKH;
Costa MP;
Holanda FGS;
Prado JWL;
Piauilino JVM;
Vilela MPC;
Neto FNM;
Maceda IO;
Dantas PHP;
Fernandes JB;
Moreira VM;
Junior MAPN;
Almeida ILX;
Farias AM;
Braga MCV;
Gomes LQ;
Silva SQ;
Pereira JVM;
Barbosa LG;
Hidalgo CR;
Aguiar KS;
Castro LRS;
Campos NMF;
Drebes B;
Araújo DS;
Ananias AYT;
Lopes CO;
Sousa MBM;
Soares ASB;
Frota EV;
Saldanha YG;
Gomes ALC;
Carvalho MS

Erika Mourão Alves Silva

Denis Kleber Holanda Guerra

Marine Praciano Costa

Flávio Gifoni Siebra de Holanda

José Walter Lima Prado

João Victor Maia Piauilino

Marcos Paulo Costa Vilela

Francisco do Nascimento Moura Neto

Isabelle Oliveira Maceda

Pedro Henrique Pinheiro Dantas

Jady Braga Fernandes

Vinícius de Medeiros Moreira

Marcio Alberto Pinto Nunes Junior

Ianne Lima Xavier de Almeida

Alesson Miranda Farias

Matheus Custódio Vieira Braga

Larissa de Queiroz Gomes

Sâmia Quirino da Silva

João Victor Marinho Pereira

Larissa Gonçalves Barbosa

Cristian Rocha Hidalgo

Kauany Sousa Aguiar

Lara Rodrigues Saunders de Castro

Natália Maria Figueiredo Campos

Bruna Drebes

David Sandro Araújo

Ana Yasmin Tomás Ananias

Clarissa Oliveira Lopes

Maria Beatriz Mendes de Sousa

Akidauanna Sales Bezerra Soares

Eduardo Vichnevski Frota

Yarla Guerra Saldanha

André Luiz Cardoso Gomes

Marilea dos Santos Carvalho


Keywords

Adverse effects of statins
Statin-induced myopathy
Management of statin-related myalgia
Interaction of vitamin D with statins

Abstract

This book chapter examines the relationship between statin use and statin-induced myalgia, emphasizing the importance of effective management strategies. It aims to identify the main symptoms, evaluate risk factors, mechanism of action and especially explore alternative treatments, including the association of statins with vitamin D. The methodology involved a descriptive and qualitative literature review focusing on databases such as Scielo, Google Scholar and PubMed, from 1996 to 2024. The results show the need for personalized approaches in treatment, considering individual variability in response to medication. It is concluded that in-depth understanding and careful management are crucial to improve treatment adherence and quality of life for patients.

 

DOI:https://doi.org/10.56238/sevened2024.005-011


Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright (c) 2024 Erika Mourão Alves Silva, Denis Kleber Holanda Guerra, Marine Praciano Costa, Flávio Gifoni Siebra de Holanda, José Walter Lima Prado, João Victor Maia Piauilino, Marcos Paulo Costa Vilela, Francisco do Nascimento Moura Neto, Isabelle Oliveira Maceda, Pedro Henrique Pinheiro Dantas, Jady Braga Fernandes, Vinícius de Medeiros Moreira, Marcio Alberto Pinto Nunes Junior, Ianne Lima Xavier de Almeida, Alesson Miranda Farias, Matheus Custódio Vieira Braga, Larissa de Queiroz Gomes, Sâmia Quirino da Silva, João Victor Marinho Pereira, Larissa Gonçalves Barbosa, Cristian Rocha Hidalgo, Kauany Sousa Aguiar, Lara Rodrigues Saunders de Castro, Natália Maria Figueiredo Campos, Bruna Drebes, David Sandro Araújo, Ana Yasmin Tomás Ananias, Clarissa Oliveira Lopes, Maria Beatriz Mendes de Sousa, kidauanna Sales Bezerra Soares, Eduardo Vichnevski Frota, Yarla Gurra Saldanha, André Luiz Cardoso Gomes, Marilea dos Santos Carvalho

Author(s)

  • Erika Mourão Alves Silva
  • Denis Kleber Holanda Guerra
  • Marine Praciano Costa
  • Flávio Gifoni Siebra de Holanda
  • José Walter Lima Prado
  • João Victor Maia Piauilino
  • Marcos Paulo Costa Vilela
  • Francisco do Nascimento Moura Neto
  • Isabelle Oliveira Maceda
  • Pedro Henrique Pinheiro Dantas
  • Jady Braga Fernandes
  • Vinícius de Medeiros Moreira
  • Marcio Alberto Pinto Nunes Junior
  • Ianne Lima Xavier de Almeida
  • Alesson Miranda Farias
  • Matheus Custódio Vieira Braga
  • Larissa de Queiroz Gomes
  • Sâmia Quirino da Silva
  • João Victor Marinho Pereira
  • Larissa Gonçalves Barbosa
  • Cristian Rocha Hidalgo
  • Kauany Sousa Aguiar
  • Lara Rodrigues Saunders de Castro
  • Natália Maria Figueiredo Campos
  • Bruna Drebes
  • David Sandro Araújo
  • Ana Yasmin Tomás Ananias
  • Clarissa Oliveira Lopes
  • Maria Beatriz Mendes de Sousa
  • Akidauanna Sales Bezerra Soares
  • Eduardo Vichnevski Frota
  • Yarla Guerra Saldanha
  • André Luiz Cardoso Gomes
  • Marilea dos Santos Carvalho