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Chemical composition of brazilian pennyroyal essential oil (Mentha pulegium L.) and evaluation of the antimicrobial effect on Staphylococcus aureus and Escherichia coli

Rosa ACR;
Lima RM;
Miranda GS;
Rangel DS;
Medeiros GS;
Alves TCO;
Couto JO;
Andrade JV;
Perin ILB;
Marques CFPM;
Verly LB;
Santos MFC

Ana Carla Rangel Rosa

Robson Moreira de Lima

Giulia Stavrakas Miranda

Deysiane da Silva Rangel

Gabriela dos Santos Medeiros

Thalita Cristyne de Oliveira Alves

Joice Olinda do Couto

João Victor Andrade

Isabelle Lucas Braga Perin

Cecília Fernandes Patta Muller Marques

Leonardo Bindelli Verly

Mário Ferreira Conceição Santos


Keywords

Antioxidant
Lamiaceae
Antibacterial properties
CBA
CG/MS

Abstract

The extraction of the EOs was first obtained by hydrodistillation, then their chemical composition was determined by GC/MS and their antimicrobial activity was evaluated. In the analysis and identification of the hydrodistilled  essential oil of Mentha pulegium L. by gas chromatography and mass spectroscopy, 12 compounds were separated, representing 99.31% of the total mass of the essential oil. The majority component was pulegone (80.553%), other components present in appreciable levels were; Piperitone (5,430%); Cyclohexanone,5-methyl-2-(1-methyl)-,(2R-cis) (3,304%); trans-Isopulegone (2.945%); α-Humulena (1,950%). In addition, the screening of the essential oil reveals that there were appreciable results regarding its antibacterial activity against S. aureus 20 μg/mL and E. coli 2.5  μg/mL  . This result was obtained by the undiluted essential oil. However, more research on the factors that influence the biosynthesis and bioactivity of essential oils is needed as essential oils gain important applications in the food and pharmaceutical industry.

 

DOI:https://doi.org/10.56238/sevened2023.001-009


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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright (c) 2023 Ana Carla Rangel Rosa , Robson Moreira de Lima , Giulia Stavrakas Miranda , Deysiane da Silva Rangel , Gabriela dos Santos Medeiros , Thalita Cristyne de Oliveira Alves , Joice Olinda do Couto , João Victor Andrade , Isabelle Lucas Braga Perin , Cecília Fernandes Patta Muller Marques , Leonardo Bindelli Verly , Mário Ferreira Conceição Santos

Author(s)

  • Ana Carla Rangel Rosa
  • Robson Moreira de Lima
  • Giulia Stavrakas Miranda
  • Deysiane da Silva Rangel
  • Gabriela dos Santos Medeiros
  • Thalita Cristyne de Oliveira Alves
  • Joice Olinda do Couto
  • João Victor Andrade
  • Isabelle Lucas Braga Perin
  • Cecília Fernandes Patta Muller Marques
  • Leonardo Bindelli Verly
  • Mário Ferreira Conceição Santos