Peters Syndrome: A diagnostic approach, clinical evolution and review
Abstract
Introduction: Peters syndrome (or Peters anomaly, or anterior segment mesenchymal dysgenesis) is a rare and congenital genetic condition, described by Arthur G. H. Peters in 1906, which affects the anterior ocular mesenchymal segment, presenting varying degrees of corneal opacity, iridocorneal synechiae, presence of anterior chamber narrowing and Descemet's membrane defect. Case Presentation: A 6-year-old boy, born in Goiânia, state of Goiás, with a term birth and no history of previous health problems, was referred to our service by a general practitioner due to reduced visual acuity (VA) problems in both eyes and strabismus. The mother, who accompanied him, reported that the symptoms of strabismus began approximately a year and a half ago. She also mentioned that she was properly vaccinated during pregnancy against infections that could cause birth defects and denied any complications during pregnancy or childbirth. There is no relevant family history of eye diseases.
Discussion: Because it is a rare anomaly, epidemiological data are scarce in the world literature, the only constant data is that the bilateral presentation is present in most cases. In this summary, we will address the main aspects of Peters syndrome, including its pathophysiology, classification, clinical characteristics, diagnosis and treatment. It is a syndrome that requires multidisciplinary evaluation to treat systemic complications, in some cases requiring a surgical approach such as penetrating keratoplasty and glaucoma treatment. Conclusion: The treatment varies according to the presentation of the condition and the genetic and multidisciplinary evaluation is of paramount importance in these patients.
DOI:https://doi.org/10.56238/sevened2023.006-143
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright (c) 2023 Amanda Mayumi Aoyagi, Isabele Ferreira da Silva , Amanda de Almeida Martins, Camilo de Lelis Lobo Ribeiro, Yasmin de Amorim Vieira, Lara Caroline Cardoso , Matheus Mendonça Domingues, André Lages Gonçalves Castelo Branco , Arianny Lima da Silva, Gabriel Cezar de Araujo Miguel, Verônika Carazzai Reisdorfer, Luana Rafaela Saldanha Bogaski, Victória Leoni Pardi de Castro, Brenda Etges Arenzon, Carolina Caetano de Araujo NunesAuthor(s)
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Amanda Mayumi Aoyagi
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Isabele Ferreira da Silva
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Amanda de Almeida Martins
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Camilo de Lelis Lobo Ribeiro
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Yasmin de Amorim Vieira
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Lara Caroline Cardoso
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Matheus Mendonça Domingues
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André Lages Gonçalves Castelo Branco
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Arianny Lima da Silva
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Gabriel Cezar de Araujo Miguel
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Verônika Carazzai Reisdorfer
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Luana Rafaela Saldanha Bogaski
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Victória Leoni Pardi de Castro
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Brenda Etges Arenzon
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Carolina Caetano de Araujo Nunes