Peripheral inflammatory neuropathy related to oral vaccine against polyomyeloitis: A case report

Abstract

At two years of age, 10 months after the 1st booster of the oral poliovirus vaccine, the pacient started with a subacute presentation of hypotrophy of the left lower limb, hyporeflexia and scarvating gait due to lack of function of the foot dorsiflexors. Cranioencephalic tomographic studies and lumbosacral spine MR were performed, ruling out anatomical alterations. In electroneuromyography examination, sciatic neuritis was observed. The patient's condition continued to evolve negatively, resulting in deformity of the foot structure and difficulty in walking less than one year after the onset of symptoms. It is not possible to state that the neuropathy was the exclusive result of an adverse reaction to the polio vaccine, however this is the most likely pathophysiological mechanism considering that other causes have been ruled out and the condition progresses with muscle paralysis typical of poliomyelitis. The present case report is important for epidemiological control and containment of virus damage.

DOI:https://doi.org/10.56238/uniknowindevolp-006