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Dietary intake of antioxidants in patients with myelodysplastic syndrome

Rodrigues AREC;
Sales AEC;
Pinheiro H;
Barros GABR;
Lopes SC;
Alexandrino RKC;
Melo PTH;
Leite LTE;
Sousa VBG;
Mendonça PS

Ana Raquel Eugênio Costa Rodrigues

Andressa Eslayne Caldas Sales

Helen Pinheiro

Gustavo André Bandeira do Rêgo Barros

Synara Cavalcante Lopes

Renata Kellen Cavalcante Alexandrino

Priscilla Taumaturgo Holanda Melo

Lília Teixeira Eufrásio Leite

Vivian Braga Gomes de Sousa

Priscila da Silva Mendonça


Keywords

Food Consumption
Micronutrients
Antioxidants
Neoplasms
Leukemia Myeloid Acute
Carcinogenesis

Abstract

Introduction: Changes in lifestyle, including eating habits, are determining factors in the possibility of protecting the body against the development of neoplastic tumors, including Myelodysplastic Syndrome (MDS). Objectives: To evaluate the usual intake of antioxidants in patients diagnosed with MDS. Methods: Cross-sectional study in a tertiary university hospital in Ceará. Participants were 102 patients with MDS and 102 healthy individuals, matched according to sex and age. Food consumption was evaluated through 2 24-hour recordings, and the nutritional orientation of the intake of antioxidant micronutrients (vitamins A, C and E and the minerals zinc, selenium and magnesium) was analyzed. Results: Most participants were female (62.7%). The mean age of patients with MDS was 72.07 years ± 11.63 and of controls was 69.24 ± 9.24 (p= 0.066). Among the MDS group, 77.5% were aged 65 years or older. The nutrients with the highest prevalence of inadequacy among patients with DMS were selenium (100.0%) and magnesium (98.0%). There was no difference in the prevalence of inadequate consumption of vitamin A, C, E, magnesium, selenium and zinc between the group with MDS and controls (p> 0.05). Patients with MDS older than 65 years had significantly lower consumption of vitamin C (p= 0.037) and selenium (p= 0.004) than the group of young patients. Conclusion: The study showed a high prevalence of inadequate consumption of antioxidant vitamins and minerals among patients with MDS and a healthy population, with emphasis on the lower intake of vitamin C and selenium associated with the group with MDS aged over 65 years.

 

DOI:https://doi.org/10.56238/Connexpemultidisdevolpfut-067


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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright (c) 2023 Ana Raquel Eugênio Costa Rodrigues, Andressa Eslayne Caldas Sales, Helen Pinheiro, Gustavo André Bandeira do Rêgo Barros, Synara Cavalcante Lopes, Renata Kellen Cavalcante Alexandrino, Priscilla Taumaturgo Holanda Melo, Lília Teixeira Eufrásio Leite, Vivian Braga Gomes de Sousa, Priscila da Silva Mendonça

Author(s)

  • Ana Raquel Eugênio Costa Rodrigues
  • Andressa Eslayne Caldas Sales
  • Helen Pinheiro
  • Gustavo André Bandeira do Rêgo Barros
  • Synara Cavalcante Lopes
  • Renata Kellen Cavalcante Alexandrino
  • Priscilla Taumaturgo Holanda Melo
  • Lília Teixeira Eufrásio Leite
  • Vivian Braga Gomes de Sousa
  • Priscila da Silva Mendonça