Innovative formulation containing tocotrienol: A proposal for a food supplement

Abstract

The global population aging trend has been studied for more than 30 years. Data indicate that the Brazilian population of elderly will be larger than that of young people by the year 2050. In the United States this phenomenon has also been observed. The human biological system most affected with aging is the central nervous system, resulting in the decrease of neurons and loss of nerve conduction velocity, limitations in motor areas and incidence of pathological events related to advancing age. In this context, science has pointed out the effectiveness of the consumption of Vitamin E and its isoforms (tocotrienols) in neuroprotection, being effective in the prevention and treatment of senile diseases. Thus, the present work aims to propose an innovative formulation containing tocotrienol of annatto (Bixa orellana) to be consumed as a food supplement. Through a bibliographic survey and online market research, the supplements containing tocotrienol available to the consumer were evaluated. These supplements, for the most part, are presented for consumption in the form of soft gel. From this study, it was possible to define a proposal for a theoretical formulation in the form of an orodispersible tablet, which was tested in the pharmacotechnical laboratories of the Biopark, enabling the elaboration of a prototype of an innovative product. As a result, it was possible to obtain samples of the product with the possibility of being marketed in the American market, where dietary supplements are sold freely in supermarkets and pharmacies.

DOI:https://doi.org/10.56238/globalhealthprespesc-009