Overweight and cardiovascular risk in patients undergoing hematopoietic stem cell transplantation

Abstract

Introduction: Hematopoietic Stem Cell Transplantation (HSCT) is a therapeutic proposal for oncohematological treatment that includes the use of high-dose chemotherapy, after carrying out the conditioning regimen, and many of these classes of antineoplastic agents have cardiotoxic effects. In addition, cardiovascular diseases are among the main causes of post-HSCT morbidity and mortality. Objectives: To assess the nutritional status and cardiovascular risk of patients admitted for HSCT.

Methods: Cross-sectional, retrospective study with an analytical component and a quantitative approach. Data was obtained from electronic medical records, from the years 2019 and 2020. Information was collected from the moment of admission, including age, gender, diagnosis, type of transplant, comorbidity report, biochemical tests, body weight, height, waist circumference (WC), and arm circumference. Results: The present study was carried out with 81 patients admitted for HSCT. There was a higher prevalence of Multiple Myeloma (34.6%, n=28) and autologous transplantation (64.2%, n=52). Systemic arterial hypertension (30.9%, n=25) was one of the most reported comorbidities by patients. Most patients were overweight (63%, n=51), high Low-Density Lipoprotein (57.8%, n=37), low High-Density Lipoprotein (58.46%, n=38), and cardiovascular risk assessed by WC (80.2%, n=65). Conclusion: It can be concluded that patients admitted for HSCT had a high prevalence of overweight and cardiovascular risk.

DOI:https://doi.org/10.56238/alookdevelopv1-123