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Basic principles in antibiotic therapy

Netto FF;
Cleto AS;
Mansani FP;
Cordeiro TMG;
Matkovsky JA;
Hanke PY;
Mainardes J;
Ferreira RRP;
Brogiatto BA;
Justus IH

Felício de Freitas Netto

André Saad Cleto

Fabiana Postiglione Mansani

Tatiana Menezes Garcia Cordeiro

Jorge Antonio Matkovsky

Polyana Yasmin Hanke

Jessica Mainardes

Rusllan Ribeiro de Paiva Ferreira

Bruno Antunes Brogiatto

Isabela Hess Justus


Keywords

Antibiotics
Prescription
Pharmacology

Abstract

In 1877, Louis Pasteur studied the phenomenon of antibiosis, that is, the disharmonious interspecific relationship; however, only years later, the first antibiotic substance was developed, in 1929, by Alexander Fleming, which consisted of a yeast-like colony that reproduced in the vicinity of a petri tree. The antimicrobial spectrum can express the range of action of the drug, that is, it expresses the percentage of bacterial groups sensitive to the drug. The resistance of microorganisms represents a phenomenon of their evolutionary adaptation, which can be natural or acquired. The increase in the number of resistant bacteria may be linked to the mechanism of "induced selection", i.e., antibiotics lyse sensitive organisms, leaving resistant ones unharmed; or through dissemination, which happens through ingestion and/or contact with foods composed of antimicrobials.

 

DOI:https://doi.org/10.56238/sevened2024.007-022


Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright (c) 2024 Felício de Freitas Netto, André Saad Cleto, Fabiana Postiglione Mansani, Tatiana Menezes Garcia Cordeiro, Jorge Antonio Matkovsky, Polyana Yasmin Hanke, Jessica Mainardes, Rusllan Ribeiro de Paiva Ferreira, Bruno Antunes Brogiatto, Isabela Hess Justus

Author(s)

  • Felício de Freitas Netto
  • André Saad Cleto
  • Fabiana Postiglione Mansani
  • Tatiana Menezes Garcia Cordeiro
  • Jorge Antonio Matkovsky
  • Polyana Yasmin Hanke
  • Jessica Mainardes
  • Rusllan Ribeiro de Paiva Ferreira
  • Bruno Antunes Brogiatto
  • Isabela Hess Justus

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