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Characterization of the manifestations of Down Syndrome in Brazil between 2016 and 2020: an epidemiological study

Shabrinna Silva Resende A;
Machado Miranda Leal Barbosa S;
Luísa Xavier Carvalho Andrade I;
Manoel Oliveira Costa L;
Moura Melo S;
Holanda Moura E;
Vinicius de Carvalho Souza M;
Andrade da Silva Junior E;
de Assis de Brito R;
Folha Gois Moreira K

Antônia Shabrinna Silva Resende

Sara Machado Miranda Leal Barbosa

Izane Luísa Xavier Carvalho Andrade

Lucas Manoel Oliveira Costa

Suely Moura Melo

Edmércia Holanda Moura

Marcus Vinicius de Carvalho Souza

Eduardo Andrade da Silva Junior

Rafael de Assis de Brito

Kellyane Folha Gois Moreira


Resumo

Objective: to relate the classifications of trisomy 21 according to the number of live births in Brazilian states between 2016 and 2020. Methodology: refers to a retrospective, descriptive study of live births with T21 that occurred between 2016 and 2020 in Brazil. The information pertinent to the preparation of the study was immediately removed from the Information System on Live Births (SINASC) of the Department of Informatics of the Unified Health System (DATASUS) of the Ministry of Health (MS). Results and discussion: it can be observed, in the three classifications of Down syndrome, the state of São Paulo with the highest percentage (149 cases corresponding to 60.82%), in the meiotic nondisjunction, and the lowest percentage is the state of Mato Grosso do Sul. south (1 case referring to 0.4%), it can be observed that the classification that presented the lowest percentage of live births was mosaicism, with São Paulo also being the state that presented the highest percentage compared to the others (45 cases referring to 46 .40%). Conclusion: This research made it possible to analyze the three classifications of trisomy at a global level, and pointed out the need to collect primary data that, as they come from existing database systems, depend on the quality of filling out the notification forms, and new research related to the theme.

 

DOI: 10.56238/pacfdnsv1-080


Creative Commons License

Este trabalho está licenciado sob uma licença Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright (c) 2023 Antônia Shabrinna Silva Resende , Sara Machado Miranda Leal Barbosa , Izane Luísa Xavier Carvalho Andrade , Lucas Manoel Oliveira Costa , Suely Moura Melo, Edmércia Holanda Moura , Marcus Vinicius de Carvalho Souza , Eduardo Andrade da Silva Junior , Rafael de Assis de Brito , Kellyane Folha Gois Moreira

##plugins.themes.gdThemes.article.Authors##

  • Antônia Shabrinna Silva Resende
  • Sara Machado Miranda Leal Barbosa
  • Izane Luísa Xavier Carvalho Andrade
  • Lucas Manoel Oliveira Costa
  • Suely Moura Melo
  • Edmércia Holanda Moura
  • Marcus Vinicius de Carvalho Souza
  • Eduardo Andrade da Silva Junior
  • Rafael de Assis de Brito
  • Kellyane Folha Gois Moreira