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Streptococcus pyogenes: A review of the combination of virulence and versatility

Sousa JY;
Castro MF;
Moreno JD;
Castro FFS

Jeannie Yokoyama de Sousa

Melina Fernandes Castro

Júlia Dias Moreno

Fabíola Fernandes dos Santos Castro


Resumen

Streptococcus pyogenes is also known as group A β-hemolytic streptococcus (SAG). Man is its only reservoir in nature, and is found asymptomatically colonizing the skin, mucous membranes of the throat, nose, nasopharynx, anus, and scalp. This bacterium affects more children, adolescents and the elderly due to poor hygiene, low immunity and secondary infections. It also has the ability to cause various forms of clinical infections and post-infectious sequelae, the most common being streptococcal pharyngitis. The main virulence factors presented by S. pyogenes are adhesion; hyaluronic acid capsule; M protein; DNAse, C5a peptidase, hyaluronidase and streptokinase enzymes; fumed exotoxins; streptolysis. Through the study of these factors it is possible to understand the versatility of this microorganism.

 

DOI:https://doi.org/10.56238/sevened2024.007-078


Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.

Derechos de autor 2024 Jeannie Yokoyama de Sousa, Melina Fernandes Castro, Júlia Dias Moreno, Fabíola Fernandes dos Santos Castro

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  • Jeannie Yokoyama de Sousa
  • Melina Fernandes Castro
  • Júlia Dias Moreno
  • Fabíola Fernandes dos Santos Castro