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Analysis of the influence of gentamicin sulfate and cooling technique on the mechanical properties of Poly (methyl methacrylate)

Cardoso PHN;
Junior DB;
Fonseca KLS;
Cordeiro ER;
Idogava HT;
Silva AC;
Hernandez LIN;
Olivier NC;
Araújo ES

Pedro Henrique Novaes Cardoso

Durval Baraúna Junior

Kaio Luan da Silva Fonseca

Erlon Rabelo Cordeiro

Henrique Takashi Idogava

Alan Christie da Silva

Luis Ivan Negrin Hernandez

Nelson Cardenas Olivier

Evando Santos Araújo


Resumen

Poly (methyl methacrylate) is a polymer widely used in various biomedical applications. In orthopedics, this polymer may be used as a structural reinforcement in fracture, aiding bone regeneration. To avoid fracture contamination, surgeons may add a certain homogeneously amount of antimicrobial to the Poly (methyl methacrylate). To prevent thermal necrosis during polymerization, which can reach up to 100° C, cooling techniques are used, to ensure the cells integrity during the process. Despite the great importance of Poly (methyl methacrylate) as a biomaterial, there is still a lack of information on the mechanical properties of this polymer, especially when there is modifications on Poly (methyl methacrylate) composition and its preparation temperature. This work aims to evaluate the influence of the addition of Gentamicin Sulfate and application of cooling technique on the mechanical behavior of Poly (methyl methacrylate) in three commercial types. For this, the mechanical tests of compression, bending and torsion were performed. With these tests it was found that, despite the reduction of the mechanical resistance of Poly (methyl methacrylate) with the cooling technique and antimicrobial addition, the polymer can still be safely used as bone cement.

 

DOI:https://doi.org/10.56238/uniknowindevolp-133


Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.

Derechos de autor 2023 Pedro Henrique Novaes Cardoso , Durval Baraúna Junior, Kaio Luan da Silva Fonseca, Erlon Rabelo Cordeiro , Henrique Takashi Idogava , Alan Christie da Silva , Luis Ivan Negrin Hernandez , Nelson Cardenas Olivier , Evando Santos Araújo

##plugins.themes.gdThemes.article.Authors##

  • Pedro Henrique Novaes Cardoso
  • Durval Baraúna Junior
  • Kaio Luan da Silva Fonseca
  • Erlon Rabelo Cordeiro
  • Henrique Takashi Idogava
  • Alan Christie da Silva
  • Luis Ivan Negrin Hernandez
  • Nelson Cardenas Olivier
  • Evando Santos Araújo