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THERAPEUTIC APPROACHES IN THE MANAGEMENT OF SEPSIS IN PATIENTS WITH INFECTIVE ENDOCARDITIS

de Santana MLP;
Ferreira ARR;
da Silva MFLC;
Barbosa ES;
Siqueira AMP;
Vieira ACGN;
Serafim ECG;
Moura FMN

Maria Lucia Pinto de Santana

Antonia Roberlene Ribeiro Ferreira

Márcia Freitas Lima Castro da Silva

Emanuelle Sales Barbosa

Andréa Maria de Paula Siqueira

Antônio Carlos Gomes do Nascimento Vieira

Edilma Casimiro Gomes Serafim

Francisco Maximiano Nunes Moura


Keywords

Endocarditis
Sepsis
Therapeutics

Abstract

Sepsis is a critical medical condition that results from the body's inadequate response to an infection, leading to potentially life-threatening organ dysfunction. This study focuses on the management of sepsis in patients with infective endocarditis, a rare but serious infection that has a high rate of complications and mortality. Analysis of the data from this systematic review indicated that the combination of antimicrobial therapy and surgical interventions can significantly improve clinical outcomes. In addition, early identification of pathogens and appropriate choice of antibiotics have been identified as crucial to the effectiveness of treatment. Collaboration between different medical specialties proved to be essential for effective management, providing a multidisciplinary approach that integrates clinical and surgical care. The results of this review provide valuable insights for clinical practice, underscoring the need for evidence-based protocols to optimize the treatment of sepsis in infective endocarditis and thus improve health outcomes for affected patients.

 

DOI: https://doi.org/10.56238/sevened2024.030-005


Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright (c) 2024 Maria Lucia Pinto de Santana, Antonia Roberlene Ribeiro Ferreira, Márcia Freitas Lima Castro da Silva, Emanuelle Sales Barbosa, Andréa Maria de Paula Siqueira, Antônio Carlos Gomes do Nascimento Vieira, Edilma Casimiro Gomes Serafim, Francisco Maximiano Nunes Moura

Author(s)

  • Maria Lucia Pinto de Santana
  • Antonia Roberlene Ribeiro Ferreira
  • Márcia Freitas Lima Castro da Silva
  • Emanuelle Sales Barbosa
  • Andréa Maria de Paula Siqueira
  • Antônio Carlos Gomes do Nascimento Vieira
  • Edilma Casimiro Gomes Serafim
  • Francisco Maximiano Nunes Moura