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Molecular mechanisms of idiopathic pulmonary fibrosis: Emerging therapeutic approaches

Araujo VS;
Siqueira AMP;
Teixeira CS;
Serafim ECG;
Gregório ÉMS;
Mello IGKA;
Mello IGKA;
Laudelino JS;
Costa SM;
Mororó SHV

Victoria Souza Araujo

Andréa Maria de Paula Siqueira

Carlos Santos Teixeira

Edilma Casimiro Gomes Serafim

Élida Maria Silva Gregório

Ihury Garofo Kennedy Anunciação de Mello

Ithalo Garofo Kennedy Anunciação de Mello

Jadson Soares Laudelino

Safira Monteiro Costa

Silvia Helena Varela Mororó


Keywords

Idiopathic Pulmonary Fibrosis
Molecular Pathogenesis
Emerging Therapies
Molecular Biology
Genomics

Abstract

Idiopathic Pulmonary Fibrosis (IPF) stands as one of the most puzzling interstitial lung diseases within respiratory medicine, marked by a relentless progression that impairs lung function. Despite its elusive etiology, recent breakthroughs in molecular biology and genomics have granted a deeper understanding of the intricate cellular and molecular pathways implicated in its pathogenesis. This paper seeks to provide a comprehensive and up-to-date insight into these molecular mechanisms, emphasizing their significance in the development of novel therapeutic approaches and intervention strategies aimed at curbing the disease's progression and enhancing the life quality of affected patients..

 

DOI: https://doi.org/10.56238/sevened2023.007-033


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Author(s)

  • Victoria Souza Araujo
  • Andréa Maria de Paula Siqueira
  • Carlos Santos Teixeira
  • Edilma Casimiro Gomes Serafim
  • Élida Maria Silva Gregório
  • Ihury Garofo Kennedy Anunciação de Mello
  • Ithalo Garofo Kennedy Anunciação de Mello
  • Jadson Soares Laudelino
  • Safira Monteiro Costa
  • Silvia Helena Varela Mororó