The interaction of caffeine on creatine absorption

Abstract

Introduction: Creatine and caffeine are food supplements used as ergogenic resources by athletes and practitioners of physical activity. In sports, caffeine has been commercialized because, besides inhibiting pain, it also helps in the development of muscle strength and improves sports performance. Creatine tends to improve high intensity and short duration exercise in sports performance and helps in the recovery period. Objective: To analyze and investigate the interaction of caffeine on creatine absorption. Methods: This article was developed from a bibliographic review in Medline, Lilacs, Ebsco and Google Academic databases, where books, magazines and articles were read.  Result: The findings are mixed and may be strongly influenced by the type of training, supplementation dose, exercise time, ingested schedule, and genetic influence that acts on fast or slow metabolization regarding the interaction of caffeine on creatine absorption.  Conclusion: Despite the justifications for combined creatine and caffeine supplementation, research directly investigating caffeine consumption during creatine loading suggested that caffeine may attenuate the effect of creatine when supplemented simultaneously. Future research with assessment intervals, the influence of the CYP1A2 gene on caffeine metabolization, and different dosages of ergogenic resources should be conducted to further clarify the issue.

DOI: 10.56238/isevmjv1n1-002